Recently, cases of Guillain Barre Syndrome and myasthenia gravis are becoming more frequent. If it attacks a human, this neurological disorder will interfere with the patient in the heavy mobilization during productive. Moreover, the longer the number of sufferers is increasing every year.
In the period 2010-2011, data on the number of Guillain Barre Syndrome patients in the RSCM as many as 48 cases of different variants. While the prevalence of myasthenia gravis is estimated around 0.5 to 14.2 cases per 100,000 people. The prevalence of autoimmune MG is estimated at 1 case of 10000-20000 people. Data on the RSCM during the period 2010-2011 there were 94 cases of MG show.
“Various forms of GBS and myasthenia gravis classification has a different clinical course, the hope of recovery, and a different treatment,” said Chairman of the Association of Physician Specialists Nerve Indonesia, Dr. Imran SpS Darma at a media gathering in the framework of the symposium theme of Peripheral Focus Symposium on Nerve Disorder Guillain-Barre and Myasthenia Gravis at Hotel Mulia, as quoted from okezone.
Doctor Darma said, cases of neurological disorders such as Guillain Barre Syndrome and myasthenia gravis are not high frequencies. The diseases also can recover completely with early diagnosis. Patients with symptoms of paralysis and other neurological disorders should be evaluated by a neurological specialist.
“Clinical examination and electrodiagnostic using the tools is done by nerve specialists can distinguish various neurological complaints like,” he said.
Dr. Hakim Manfaluthy SpS (K), Head of the Division of Clinical Neurophysiology and Neuromuscular Disease, Department of Neurology Faculty of Medicine explained, GBS is an immunological disorder that causes abnormalities of the peripheral nerves, causing paralysis of the extremities is ascending and symmetrical. Guillain Barre Syndrome is a disorder that causes common neuroimunologi flacid paralysis after polio era.
Early symptoms of Guillain Barre Syndrome patients, he added, is the feeling of numbness that radiates from the ends of fingers and toes, to spread to other parts of the body that ultimately result in paralysis.
“To diagnose Guillain Barre Syndrome, in addition to the neurological disorders symptoms and cerebrospinal fluid analysis, also performed EMG and nerve between the speed at which will provide information on early symptoms of the disease,” said Manfaluthy.
Meanwhile, myasthenia gravis is an autoimmune disorder that damages the muscle nerve Jointed resulting in muscle weakness. The cause is related to disorders of the immune system. In patients with MG, their immune system produces antibodies that attack one type of receptor at the neuromuscular jointed so that an interruption in the transmission of nerve-muscle, which result in disruption of muscle contraction.
Manfaluthy suggests, the symptoms of myasthenia gravis in general is in the form of intermittent weakness, fatigue and weakness arises as to improve after resting or when I wake up. Patients will experience reduced eyelid on one eye or both eyes and double vision. In the common type of MG, the patient felt a weakness in most of the muscles of the body.
“myasthenia gravis needs serious attention because about 15-20% of patients at risk of experiencing episodes of life-threatening myasthenia crisis in two years after diagnosis,” he said.
Recovery, improvement, and patient outcome is determined by the rate of neurological abnormalities in providing therapy. Thus, the need to make a diagnosis as early as possible. Type of therapy recommended in patients with Guillain Barre Syndrome is currently giving intravenous immunoglobulin (IVIG) and plasmapharesis (making antibodies that destroy the way of blood plasma replacement). Myasthenia gravis patients on therapy, it is known that the symptoms of MG but allegedly associated with autoimmune diseases, also associated with the thymus gland which should disappear after a childhood.
In some people, persistent thymus gland will grow into a form of benign tumor (thymoma). In patients with MG with thymoma, surgery is recommended for the removal of the tumor, in addition to taking medication regularly as directed by your doctor. Types of drugs commonly taken is pyridostigmin bromide in tablet form. Furthermore, myasthenia gravis patients should also pay attention to some of the factors that may aggravate symptoms such as fatigue due to excessive physical activity, the air is very hot, and others.
Dr. Darma said, constraint handling Guillain Barre Syndrome and myasthenia gravis is a relatively expensive medical bills. Until recently, government and private insurers do not want to bear the treatment of disease caused by neurological disorders completely.